Kualifikasi Piala Dunia 2022 zona Eropa melangsungkan beberapa laga pada Rabu (31/3/2021) dinihari WIB. Beberapa tim besar seperti Belanda, Belgia, Kroasia, Portugal, mendapatkan kemenangan. Berikut hasil laga kualifikasi Piala Dunia 2022 zona Eropa beserta klasemen sementara.
Hasil Laga (31/3/2021)
Luksemburg 1-3 Purtugal
Belgia 8-0 Belarusia
Wales 1-0 Rep Ceko
Gibraltar 0-7 Belanda
Turki 3-3 Latvia
Montenegro 0-1 Norwegia
Kroasia 3-0 Malta
Slowakia 2-1 Rusia
Klasemen Sementara
Grup A
| Tim | Main | Nilai |
| Portugal | 3 | 7 |
| Serbia | 3 | 7 |
| Luksemburg | 2 | 3 |
| Rep Irlandia | 2 | 0 |
| Azerbaijan | 2 | 0 |
Grup B
| Tim | Main | Nilai |
| Swedia | 2 | 6 |
| Spanyol | 2 | 4 |
| Yunani | 1 | 1 |
| Georgia | 2 | 0 |
| Kosovo | 1 | 0 |
Grup C
| Tim | Main | Nilai |
| Italia | 2 | 6 |
| Swiss | 2 | 6 |
| Lithuania | 1 | 0 |
| Irlandia Utara | 1 | 0 |
| Bulgaria | 2 | 0 |
Grup D
| Tim | Main | Nilai |
| Prancis | 2 | 4 |
| Finlandia | 2 | 2 |
| Ukraina | 2 | 2 |
| Bosnia&Herzegovina | 1 | 1 |
| Kazakhstan | 1 | 0 |
Grup E
| Tim | Main | Nilai |
| Belgia | 3 | 7 |
| Rep Ceko | 3 | 4 |
| Wales | 2 | 3 |
| Belarusia | 2 | 3 |
| Estonia | 2 | 0 |
Grup F
| Tim | Main | Nilai |
| Denmark | 2 | 6 |
| Austria | 2 | 4 |
| Skotlandia | 2 | 2 |
| Kep Faroe | 2 | 1 |
| Israel | 2 | 1 |
| Moldova | 2 | 1 |
Grup G
| Tim | Main | Nilai |
| Turki | 3 | 7 |
| Belanda | 3 | 6 |
| Montenegro | 3 | 6 |
| Norwegia | 3 | 6 |
| Latvia | 3 | 1 |
| Gibraltar | 3 | 0 |
Grup H
| Tim | Main | Nilai |
| Kroasia | 3 | 6 |
| Rusia | 3 | 6 |
| Slowakia | 3 | 5 |
| Siprus | 3 | 4 |
| Slovenia | 3 | 3 |
| Malta | 3 | 1 |
Grup I
| Tim | Main | Nilai |
| Inggris | 2 | 6 |
| Polandia | 2 | 4 |
| Hungaria | 2 | 4 |
| Albania | 2 | 3 |
| Andorra | 2 | 0 |
| San Marino | 2 | 0 |
Grup J
| Tim | Main | Nilai |
| Jerman | 2 | 6 |
| Armenia | 2 | 6 |
| Macedonia Utara | 2 | 3 |
| Rumania | 2 | 3 |
| Islandia | 2 | 0 |
| Liechtenstein | 2 | 0 |
